Karl Andreas KARLSSON;Frank HALLEY;Fabienne THOMPSON;Laurent SCHIO;Jean-Christophe CARRY;Victor CERTAL
发明人:
Jean-Christophe CARRY,Victor CERTAL,Frank HALLEY,Karl Andreas KARLSSON,Laurent SCHIO,Fabienne THOMPSON
申请号：
US13338011
公开号：
US20120270867A1
申请日:
2011.12.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to the novel materials of formula (I), where: R1 is an optionally substituted aryl or heteroaryl； R is an H or, when formed with R1, a 5- or 6-member ring fused with an aryl or heretoaryl group optionally containing one or more of O, S, N, NH, and Nalk, being optionally substituted； R2 and R3 are, independently, an H, Hal, or alkyl optionally substituted by one or more Hal； R4 is H； and R5 is an H or alkyl optionally substituted by one or more halogen atoms. Said materials being in any isomeric form and the salts thereof, and are intended for drugs, particularly AKT(PKB) phosphorylation inhibitors.
