A blood purification column includes a cylindrical body, a first header having a first blood channel, a second header having a second blood channel, an adsorbent carrier, a first end plate, a second end plate, and a blood flow tube, wherein: one end of the blood flow tube communicates with the first blood channel and the other end is closed the first end plate has its outer circumferential surface closely contacting the inner circumferential surface of the cylindrical body a gap is provided between the outer circumferential surface of the second end plate and the inner circumferential surface of the cylindrical body the ratio of the outer diameter of the blood flow tube in the cross-section vertical to the longitudinal direction, to the inner diameter of the cylindrical body in the cross-section vertical to the longitudinal direction, is 0.35 to 0.50 and the blood capacity is 6 to 10 mL.
