The California Institute for Biomedical Research;The Scripps Research Institute
发明人:
Chanhyuk Kim,Jun Y. Axup,Hwayoung Yun,Peter G. Schultz,Jennifer Ma,Jiayin Shen,Pengyu Yang
申请号:
US14774647
公开号:
US10351626B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.