Tatyana Timiryasova;Qian Zhang;Aladar A. Szalay;Yong A. Yu
发明人:
Aladar A. Szalay,Tatyana Timiryasova,Yong A. Yu,Qian Zhang
申请号:
US14301813
公开号:
US20140294891A1
申请日:
2014.06.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Therapeutic methods and vaccinia virus therefor are provided. The viruses are designed so that they accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. Combinations of the viruses and anti-cancer agents and uses thereof for treating cancer also are provided