A method and system for treating sepsis/septic shock by increasing whole body blood flow. A method and protocol for application of neuromuscular electrical stimulation (NMES) to the skeletal muscles using a plurality of treatment pads (electrodes) on one or more limbs, activated sequentially, with overlapping timing, distal to proximal, with the impulses released in a similar, following pattern to enhance the refill cycle, resulting in accelerated wave-form blood flow in cardiovascular circulation.