The invention relates toa tissue receiving bag for use in surgery, especially laparoscopie surgery, wherein the bag camprises at least one tissue receiving opening for receiving tissue andlor an instrument opening, especially a moreeliator opening, wherein the bag camprises at least one further opening into the bag, wherein a flexible tube extends from said further opening having a free end comprising an insertion opening for inserting an instrument into the bag, wherein the bag preferably is inflatable.