This present invention provides a method for continuously maintaining growth of a motor neuron progenitor cell and a pharmaceutical composition. Wherein, the method for continuously maintaining growth of a motor neuron progenitor cell is to culture the motor neuron progenitor cell in an environment which is constructed by the olfactory ensheathing cells to make the motor neuron progenitor cell sustain the ability to self-replicate and to be induced for differentiating into mature neuron, and therefore to elaborate the effect to protect the motor neuron. The motor neuron progenitor cell produced from the method disclosed in this present invention can be an effective ingredient of the pharmaceutical composition for treating related diseases of damaged motor neuron.本發明係在於提供一種持續維持運動神經元前驅細胞生長之方法及醫藥組合物，其中，該持續維持運動神經元前驅細胞生長之方法透過將運動神經元前驅細胞培養於一由嗅神經髓鞘細胞所建構之環境中，使運動神經元前驅細胞長期地維持自我複製以及得以被誘導分化為成熟神經元之能力，據以有效地發揮對於運動神經元之保護作用。藉由本發明所揭方法得到之運動神經元前驅細胞，係能夠作為治療運動神經元受損相關疾病之醫藥組合物之有效成份。
