IBRAHIM PRABHA N,ZHANG CHAO,ZHANG JIAZHONG,BOLLAG GIDEON,HABETS GASTON,WU GUOXIAN
申请号:
NZ61752612
公开号:
NZ617526A
申请日:
2012.05.17
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed is the use of [5-(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-(6-trifluoromethyl-pyridin-3-ylmethyl)-amine (pexidartinib) in the manufacture of a medicament for treating acute myeloid leukaemia (AML) in a subject wherein the subject has an FMS-like tyrosine kinase (Flt3) gene with an internal tandem duplication (ITD) mutation.