Janet C. Blanks,Howard M. Prentice,C. Kathleen Dorey
申请号：
US13246527
公开号：
US08785413B2
申请日:
2011.09.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and diabetic retinopathy. In preferred embodiments, the subject invention provides materials and methods for effective treatment of pathological ocular neovascularization using gene therapy. In a specific embodiment the materials and methods of the subject invention can be used to treat AMD.
