C14-位羥基酯化的雷公藤甲素氨基酸衍生物、及其製備方法和應用

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专利权人:

HANGZHOU WEBEN PHARMACEUTICALS INC.

发明人:

XU, Rongzhen,JIANG, Hongjian

申请号：

HK18105555.6

公开号：

HK1246279A

申请日:

2018.04.28

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

The present invention belongs to the field of natural medicines and medicinal chemistry, and relates to novel esterified amino acid derivatives of triptolide of general formula I and general formula II or pharmaceutically acceptable adducts, complexes, salts, and catabolites and metabolites thereof, preparation methods of these compounds, pharmaceutical compositions comprising the compound, and uses thereof in preparing drugs against tumors, immune diseases, or diseases related to abnormal expression of XPB or Pol II or oncogene c-myc.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/