CO-CRYSTALS OF TRAMADOL AND COXIBS

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专利权人:

LABORATORIOS DEL DR. ESTEVE; S.A

发明人:

PLATA SALAMAN, CARLOS, RAMON,TESSON, NICOLAS

申请号：

MYPI 2012000675

公开号：

MY156285A

申请日:

2010.04.19

申请国别(地区):

MY

年份:

2016

代理人:

摘要：

THE PRESENT INVENTION RELATES TO CO-CRYSTALS OF TRAMADOL AND CO-CRYSTAL FORMERS SELECTED FROM NSAIDS/COXIBS, PROCESSES FOR PREPARATION OF THE SAME AND THEIR USES AS MEDICAMENTS OR IN PHARMACEUTICAL FORMULATIONS, MORE PARTICULARLY FOR THE TREATMENT OF PAIN. IN A PREFERRED EMBODIMENT, THE CO-CRYSTAL IS (RAC) - TRAMADOL. HCL - COLOCOXIB (1:1). (THE MOST ILLUSTRATIVE DRAWING IS FIGURE 1)

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