POLY

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专利权人:

发明人:

JAYARAMAN NARAYANASWAMY,THANKAPPAN PADINJAREMATTATHIL ULLAS,MADHUSUDANA NARAYAN SHAMPUR,DESAI ANITA,JAYAMURUGAN GOVINDASAMY,YAMAJALA BHASKARA RAMA DURGA RAJESH

申请号：

IN4010/CHE/2010

公开号：

IN2010CH04010A

申请日:

2010.12.29

申请国别(地区):

IN

年份:

2014

代理人:

摘要：

Non-viral poly(ether imine) (PETIM) dendrimers based gene delivery systems is disclosed herein, wherein the PETIM dendrimer constituted with tertiary amine branch points, n-propyl ether linkers and primary amines, with and without further functionalizations, at their peripheries, exhibits significantly reduced toxicities, over a broad concentration range. The dendrimer complexes pDNA effectively, protects DNA from endosomal damages and delivers to cell nucleus.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/