NOVARTIS AG;NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.
发明人:
申请号:
IL23097214
公开号:
IL230972A
申请日:
2014.02.13
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
The invention provides novel pyrimidine and pyridine derivatives of formula (1) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.