Anne Kristin Holmeide;Ragnar Hovland;Morten Brændvang
发明人:
Anne Kristin Holmeide,Ragnar Hovland,Morten Brændvang
申请号：
US13054212
公开号：
US08759558B2
申请日:
2009.07.13
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to lipid compounds of the general formula (I):wherein R1 is selected from a C10-C22 alkyl, a C10-C22 alkenyl having 1-6 double bonds, and a C10-C22alkynyl having 1-6 triple bonds； R2 and R3 are the same or different and may be selected from a group of different substituents； Y is selected from sulphur, sulfoxide, and sulfone； and X represents a carboxylic acid or a derivative thereof, a carboxylic ester, a carboxylic anhydride or a carboxamide； or a pharmaceutically acceptable salt, complex or solvate thereof.The invention also relates to pharmaceutical compositions and lipid compositions comprising such compounds, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic and inflammatory disease area.
