CONRAD, ANDREW JASON,PEETERS, ERIC,BAJAJ, VIKRAM SINGH,THOMPSON, JASON DONALD,ASKEW, MARK
申请号：
CA2928147
公开号：
CA2928147A1
申请日:
2014.10.22
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
A method for modulating a response signal includes introducing functionalized particles into a lumen of subsurface vasculature, wherein the functionalized particles are configured to interact with one or more target analytes present in blood circulating in the subsurface vasculature； and non-invasively detecting the one or more target analytes. A response signal, which may include a background signal and an analyte response signal related to interaction of the functionalized particles with the one or more target analytes, is transmitted from the subsurface vasculature. A modulation configured to alter the response signal such that the analyte response signal is affected differently than the background signal may be applied to a portion of subsurface vasculature. Analyte detection may be achieved by differentiating the analyte response signal from the background signal.
