Xiao, Shouhua,Pan, Zheng,Wickramasinghe, Dineli,Jeffries, M. Shawn,King, Chadwick Terence,Chan, Brian Mingtung,Kufer, Peter,Lutterbuese, Ralf,Raum, Tobias,Hoffmann, Patrick,Rau, Doris,Kischel, Roman,L
申请号：
HRP20191983
公开号：
HRP20191983T1
申请日:
2019.10.31
申请国别(地区):
HR
年份:
2020
代理人:
摘要：
The present invention provides to a antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target cell and a second domain capable of binding to human CD3 on the surface of a T cell. Moreover, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention relates a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
