The present invention relates to ophthalmic compositions for treatment of conditions in the eye. More specifically, the present invention relates to ophthalmic compositions comprising a polyquaternium compound and an anionic polymer. Methods for reducing and/or preventing the incompatibility of polyquaternium compounds with anionic polymers are also disclosed.本發明有關用以治療眼睛病症的眼用組成物。詳言之,本發明有關眼用組成物,其包含聚四級銨(polyquaternium)化合物及陰離子性聚合物。亦揭示用以減少及/或防止聚四級銨化合物與陰離子性聚合物之間的不相容性之方法。