PROCÉDÉ DE PRODUCTION DE GLYCOPROTÉINES RECOMBINÉES PRÉSENTANT UNE DEMI-VIE CIRCULANTE ACCRUE DANS DES CELLULES DE MAMMIFÈRE

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专利权人:

The Johns Hopkins University

发明人:

申请号：

EP12731900.2

公开号：

EP2661492B1

申请日:

2012.01.06

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Provided herein are methods and recombinant expression systems for the production of recombinant glycoproteins that have increased sialic acid content and contain predominantly alpha2-6 sialic acid linkages. Also provided herein are recombinant glycoproteins that have an increased in vivo circulatory half-life. One potential application of the glycoproteins described herein is for the treatment and prophylaxis of poisoning by neurotoxins.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/