HONG YUNHAI,홍, 윤하이,XUE YING,슈에, 잉,SHA LIXIN,사, 리신,JI XIAOMING,지, 샤오밍
申请号：
KR1020147011190
公开号：
KR1020140069273A
申请日:
2012.09.25
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
Disclosed is a low impurity content caspofungin pharmaceutical composition and a method for preparing the low impurity content caspofungin pharmaceutical composition. The caspofungin pharmaceutical composition comprises the compound of formula I and/or a pharmaceutically acceptable salt thereof, in combination with a saccharide protective agent(s) and an amino acid(s). The caspofungin pharmaceutical composition is prepared by dissolving the saccharide protective agent and the amino acid into water or a suitable buffer solution adding the caspofungin compound and dissolving it filtering the solution and lyophilizing.본 발명은 불순물 함량이 낮은 카스포펀진 약학 조성물 및 이런 불순물 함량이 낮은 카스포펀진 약학 조성물의 제조방법에 대하여 공개하였다. 본 발명이 제공한 카스포펀진 약학 조성물은 양호한 안정성을 가지고 있다.
