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ADHESIVE COMPOSITION FOR CARRYING THERAPEUTIC AGENTS AS DELIVERY VEHICLE ON COATING APPLIED TO VASCULAR GRAFTS
专利权人:
The University of Tennessee Research Foundation
发明人:
Omran R. Abul-Khoudoud,Catherine Cagiannos,Waldemar DeRijk,Timothy Fabian,Lisa Jennings
申请号:
US14828418
公开号:
US20160206600A1
申请日:
2015.08.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.
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