BERG, Kristian,HØGSET, Anders,MASSON, Már,GAWARE, Vivek S.
申请号：
ES13725109
公开号：
ES2682762T3
申请日:
2013.05.14
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A compound comprising a conjugate of a photosensitizer and chitosan, wherein said compound is a compound of Formula (I): ** Formula ** in which n is an integer greater than or equal to 10, preferably an integer number of 10 to 100, R appears n times in said compound and in 0.5% -99.5% of said total Rn groups, each R is a group A selected from: H, ** Formula ** in which a is 1, 2, 3, 4 or 5； and X is Br, Cl or OH, ** Formula **； wherein each R1, which may be the same or different, is selected from H, CH3 and - (CH2) c-CH3； b is 1, 2, 3, 4 or 5； and c is 0, 1, 2, 3, 4 or 5, ** Formula **； in which Y is O； S； SO2. -NCH3, or -N (CH2) eCH3. d>； = 1, 2, 3, 4 or 5； and e>； = 1, 2, 3, 4 or 5；, ** Formula ** in which R2 is - (CH2) h-CH3 or -CO- (CH2) h-CH3； f is 1, 2, 3, 4 or 5； g is 1, 2, 3, 4 or 5； and h is 0, 1, 2, 3, 4 or 5；, ** Formula ** in which R3 is - (CH2) j-CH3, i is an integer from 1 to 200, preferably 1-10； j is 0, 1, 2, 3, 4 or 5； and k is 1, 2, 3, 4 or 5； ** Formula ** in which R3 is - (CH2) j-CH3, i is an integer from 1 to 200, preferably 1-10； and j is 0, 1, 2, 3, 4 or 5； ** Formula ** in which R3 is - (CH2) j-CH3, i is an integer from 1 to 200, preferably 1-10； j is 0, 1, 2, 3, 4 or 5； and ** Formula ** each R1, which may be the same or different, is selected from H, CH3 and - (CH2) c-CH3； and c is 0, 1, 2, 3, 4 or 5； ** Formula ** in which R3>； = - (CH2) j-CH3, i is an integer from 1 to 200, preferably 1-10； and j is 0, 1, 2, 3, 4 or 5； ** Formula ** in which R3>； = - (CH2) j-CH3, i is an integer from 1 to 200, preferably 1-10； L is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10； and j is 0, 1, 2, 3, 4 or 5； ** Formula ** and in which m is 1, 2, 3, 4 or 5； in which each group R may be the same or different； and ** Formula ** in 0.5% -99.5% of said total Rn groups, each R is a group B selected from: ** Formula ** in which p is 0, 1, 2, 3, 4 or 5； q is 1, 2, 3, 4 or 5； and r is 1, 2, 3, 4 or 5； R4 is a group selected from: ** Formula ** W is a group selected from O
