Adam De La Zerda;Victor L. Perez;Richard M. Awdeh;Sanjiv Gambhir
发明人:
Richard M. Awdeh,Victor L. Perez,Adam De La Zerda,Sanjiv Gambhir
申请号：
US13328207
公开号：
US20120213704A1
申请日:
2011.12.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Systems and methods of characterizing biological tissues are provided. In the systems and methods, a first optical coherence tomography (OCT) image of a selected portion of biological tissues combined with a plurality of nanoparticles is obtained, where the plurality of nanoparticles are configured to bind to one or more types of biological molecules in the biological tissues and to produce contrast during OCT imaging. The systems and methods also include estimating a first distribution of the plurality of nanoparticles in the selected portion based on the first OCT image and characterizing the selected portion with respect to the types of biological molecules based on the distribution.
