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Decoding approaches for protein identification
专利权人:
Inc.;Nautilus Biotechnology
发明人:
PATEL, Sujal M.,MALLICK, Parag,EGERTSON, Jarrett D.
申请号:
AU2018395430
公开号:
AU2018395430A1
申请日:
2018.12.28
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
Methods and systems are provided for accurate and efficient identification and quantification of proteins. In an aspect, disclosed herein is a method for identifying a protein in a sample of unknown proteins, comprising receiving information of a plurality of empirical measurements performed on the unknown proteins; comparing the information of empirical measurements against a database comprising a plurality of protein sequences, each protein sequence corresponding to a candidate protein among a plurality of candidate proteins; and for each of one or more of the plurality of candidate proteins, generating a probability that the candidate protein generates the information of empirical measurements, a probability that the plurality of empirical measurements is not observed given that the candidate protein is present in the sample, or a probability that the candidate protein is present in the sample; based on the comparison of the information of empirical measurements against the database.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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