KHUSIAL, PERMANAN RAAJ,SANTHANAM, UMA,LYGA, JOHN W.
申请号:
CA3010395
公开号:
CA3010395A1
申请日:
2011.11.21
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Methods for preventing, ameliorating, or reducing dermatological signs ofaging areprovided which employ active agents that suppress or down-regulate microRNAexpression indermal fibroblast, resulting in enhanced production of collagen, elastinand/or fibrillin in theskin. Also provided are methods for screening for activity against specificmicroRNAs and themethods of using active agents identified by the screening protocol in thetreatment of skin.