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COATED TABLET FORMULATION AND METHOD
专利权人:
ASTRAZENECA AB
发明人:
DIVYAKANT S. DESAI,BING V. LI
申请号:
PT10179007
公开号:
PT2298288T
申请日:
2005.05.26
申请国别(地区):
PT
年份:
2016
代理人:
摘要:
A coated tablet formulation is provided which includes a medicament such as the DPP4-inhibitor, saxaglipitin, formula (I), or its HCl salt, which is subject to intra-molecular cyclization, which formulation includes a tablet core containing one or more fillers, and other conventional excipients, which tablet core includes a coating thereon which may include two or more layers, at least one layer of which is an inner seal coat layer which is formed of one or more coating polymers, a second layer of which is formed of medicament which is the DPP4-inhibitor and one or more coating polymers, and an optional, but preferable third outer protective layer which is formed of one or more coating polymers. A method for forming the coated tablet is also provided.
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