Compounds capable of or usable in inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g. cell migration and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration and/or inhibiting a kinase and/or in treating a disease or disorder associated with an activity of a kinase such as cancer and inflammatory diseases and disorders are provided herein. The compounds are collectively represented by Formulae (Ia) or (Ib): wherein A B D E G and R1-R5 are as defined in the specification.