A compact medical device for tissue welding is provided. The hand-held plasma heads are configured for deep cuts and long cuts. A bio-compatible liquid capable of solidifying in response to application of plasma, such as an albumin solution, is applied to the wound. Plasma created from a gas such as helium is then applied to said bio-compatible liquid to solidify it and seal the wound. An additional polymerizing gas may also be applied. A feedback mechanism may maintain the temperature of said plasma. A wiper fort removal of excess liquid may also be provided.