Patrick Henry Beusker,Franciscus Marinus Hendrikus De Groot
申请号:
US11997981
公开号:
US08158590B2
申请日:
2006.08.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention relates to compounds comprising one or more therapeutic and/or diagnostic moieties and one or more functional moieties linked together via one or more triazole-containing linkers and to their intermediates and methods of their preparation. The triazole-containing linker may optionally contain one or more conditionally-cleavable or conditionally-transformable moieties and one or more spacer systems in between said moiety/moieties and the one or more therapeutic and/or diagnostic moieties.