Opko Ireland Global Holdings, Ltd.;Opko Renal, LLC
发明人:
TABASH, Samir,BISHOP, Charles,MELNICK, Joel,MESSNER, Eric,PETKOVICH, P.,WHITE, Jay
申请号:
LT11763340
公开号:
LT2552484T
申请日:
2011.03.29
申请国别(地区):
LT
年份:
2020
代理人:
摘要:
Methods and compositions for reducing serum parathyroid levels in, for example, chronic kidney disease patients are disclosed. In these methods, an effective amount of a modified release formulation of 25-hydroxyvitamin D is orally administered to a patient suffering from secondary hyperparathyroidism to lower the patient's serum intact parathyroid hormone (iPTH) level, while avoiding a surge in serum total 25-hydroxyvitamin D.