經由β-丙內酯處理的殘留細胞DNA水平降低的細胞衍生病毒疫苗

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专利权人:

NOVARTIS AG

发明人:

GREGERSEN, JENS-PETER J-P,KOST, HOLGER H,．科斯特,.格雷格森,.科斯特

申请号：

HK09107245.9

公开号：

HK1129837B

申请日:

2009.08.07

申请国别(地区):

HK

年份:

2015

代理人:

摘要：

The present invention relates to vaccine products for the treatment or prevention of viral infections. Further provided are methods of reducing contaminants associated with the preparation of cell culture vaccines. Residual functional cell culture DNA is degraded by treatment with a DNA alkylating agent, such as ²-propiolactone (BPL), thereby providing a vaccine comprising immunogenic proteins derived from a virus propagated on cell culture, substantially free of residual functional cell culture DNA.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/