Geert W. Schmid-Schonbein;Jeng Wei;Marisol Chang;Pedro Cabrales;Yung-Tsai Lee
发明人:
Geert W. Schmid-Schonbein,Yung-Tsai Lee,Jeng Wei,Marisol Chang,Pedro Cabrales
申请号：
US13825779
公开号：
US20130310325A1
申请日:
2011.09.23
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The inventors have unexpectedly discovered that shock and/or potential multi-organ failure due to shock can be effectively treated by administration of liquid high-dose protease inhibitor formulations to a location upstream of where pancreatic proteases are introduced into the gastrointestinal tract. Most preferably, administration is directly to the stomach, for example, via nasogastric tube under a protocol effective to treat shock by such administration without the need of providing significant quantities of the protease inhibitor to the jejunum and/or ileum.
