Substituted Alkyl Carboxylic Acid Derivatives As GPR Agonists农业专利-农业学术服务平台

发明人:: SHARMA, RAJIV,夏尔玛拉嘉夫,夏爾瑪拉嘉夫,HALDER, SOMNATH,哈尔德尔索姆纳特,哈爾德爾索姆納特,KUMAR, SANJAY,库马桑杰,庫馬桑傑

摘要：: The present invention relates to substituted alkyl carboxylic acid derivatives (the compounds of Formula (I)), processes for their preparation, pharmaceutical compositions containing said compounds, their use as GPR (G-protein coupled receptor) agonists, particularly as GPR40 agonists and methods of using these compounds in the treatment of GPR40 mediated diseases or conditions.本發明係相關於取代烷基羧酸衍生物(化學式(I)之化合物)、其製備程序、包含該化合物的藥學組成物、其作為GPR(G蛋白偶聯受體)促效劑,特別是作為GPR40促效劑的用途,以及將這些化合物使用於GPR40媒介疾病或症狀之治療的方法。