Formulacja zawierajaca wirus ospy, sposób jej otrzymywania i zastosowanie

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专利权人:

BAVARIAN NORDIC A/S

发明人:

HOWLEY PAUL,HELLER KARL,RAETHE INGMAR,RÄTHE INGMAR

申请号：

PL36995402

公开号：

PL213326B1

申请日:

2002.11.28

申请国别(地区):

PL

年份:

2013

代理人:

摘要：

The present invention relates to a formulation, in particular an aqueous formulation comprising (i) a poxvirus of one of the genera orthopoxvirus, avipoxvirus, parapoxvirus, capripoxvirus and suipoxvirus, (ii) a disaccharide, (iii) a pharmaceutically acceptable polymer and optionally (iv) a buffer. The aqueous formulation is particularly suitable for freeze drying processes resulting in a stable, freeze-dried, poxvirus containing composition. The invention further concerns a method for preparing a freeze-dried, poxvirus containing composition and the thus obtained product.

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