PRODRUG USING NITROIMIDAZOLE

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专利权人:

UNIVERSITY OF TSUKUBA

发明人:

NAGASAKI, YUKIO,IKEDA, YUTAKA,HISANO, HIKARU

申请号：

EP13748732

公开号：

EP2816036A4

申请日:

2013.02.13

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

Provided is a prodrug of 2-nitro-1-imidazolepropionic acid and a therapeutically active organic compound having on the molecule an amino group, a cyclic amino group or a hydroxyl group, particularly a prodrug in which the therapeutically active organic compound is selected from among antitumor agents. The prodrug cleaves specifically under hypoxic conditions in vivo to exhibit the inherent therapeutic activity.

来源网站：

中国工程科技知识中心

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