PROBLEM TO BE SOLVED: To provide an aquaporin 5 development promoter which is useful as a medicine for preventing and/or treating diseases caused by aquaporin 5 dysfunctions, such as thirst, dry eyes, and hemorrhages accompanying nasal dryness, itch sense caused by skin dryness, or pulmonary edema.SOLUTION: This aquaporin 5 development promoter contains retinoic acid or its salt as an active ingredient. The medicine for preventing and/or treating diseases caused by aquaporin 5 dysfunctions contains retinoic acid or its salt as an active ingredient.COPYRIGHT: (C)2008,JPO&INPIT【課題】口渇、ドライアイ、鼻腔乾燥に伴う出血、皮膚乾燥による掻痒感、気道乾燥による咳及び痰、又は肺水腫などのアクアポリン5の機能異常に起因する疾患の予防及び/又は治療のための医薬として有用なアクアポリン5の発現亢進剤を提供すること。【解決手段】レチノイン酸又はその塩を有効成分として含む、アクアポリン5の発現亢進剤。【選択図】なし
