Itzia Z. Arroyo,Davida Krueger,Ping Chen,Aaron J. Moment,Tesfaye Biftu,Faye Sheen,Yanfeng Zhang
申请号：
US14507001
公开号：
US09181262B2
申请日:
2014.10.06
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Novel crystalline forms of (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine are potent inhibitors of dipeptidyl peptidase-IV and are useful for the treatment of non-insulin dependent (Type 2) diabetes mellitus. The invention also relates to pharmaceutical compositions containing these novel forms, processes to prepare these forms and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes.
