COX, CHRISTOPHER D.,BESHORE, DOUGLAS C.,KIM, JUNE J.,KUDUK, SCOTT D.,MCVEAN, CAROL,REGER, THOMAS,STEEN, JUSTIN T.
申请号:
CA2851082
公开号:
CA2851082A1
申请日:
2012.10.01
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention is directed to substituted azetidinecompounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.