The present invention relates to methods of reducing cardiotoxicity and/or improving survival from treatment with anthracycline agents comprising administering a therapeutically effective amount of a composition comprising a vasopressin antagonist compound or a pharmaceutically acceptable salt thereof as an active ingredient, administered simultaneously or prior to the anthracycline administration.本發明關於減少因接受蒽環類抗生素試劑治療造成之心血管毒性和/或改善存活率之方法，其包含投予治療有效量之含有升壓素拮抗劑化合物或其醫藥上可接受之鹽作為活性成分之組成物，其係在蒽環類抗生素投予的同時或之前投予。
