INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES;FUNDACAO CALOUSTE GULBENKIAN
发明人:
DOMINGOS, ANA,BERNARDES, GONCALO
申请号:
CA3078418
公开号:
CA3078418A1
申请日:
2018.10.08
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
This invention relates to the finding that the inhibition of solute carrier family 6 member 2 (Slc6a2) exert a sympathomimetic effect outside the brain that promotes weight loss without concomitant hypophagia or hyperkinesia. Compounds for the inhibition of Slc6a2 outside the brain, as well as methods of promoting weight loss and treating obesity using such compounds are provided.