A nutritional composition including no greater than about 7 g/100 kcal of a fat or lipid source; no greater than about 7 g/100 kcal of a protein or protein equivalent source; at least about 5 g/100 kcal of a carbohydrate; and at least about 9 mg/100 kcal of inositol, wherein the inositol comprises exogenous inositol and inherent inositol, and wherein the ratio of exogenous inositol to inherent inositol is at least 75:25.