Susan BARNETT,Marguerite Christine KOUTSOUKOS,Clarisse Marie-Madeleine LORIN,Frederick PORTER,Zihao WANG,Ying ZHANG
申请号:
US16061729
公开号:
US20180360949A1
申请日:
2016.12.16
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides, inter alia, compositions useful for, e.g., raising an immune response to HIV-1, and associated methods of raising an immune response to HIV in a mammalian subject. In some embodiments, the compositions are bivalent immunogenic compositions comprising two (or, in some embodiments more than two) human immunodeficiency virus (HIV) clade C envelope gp120 polypeptide antigens, together with a liposome-based adjuvant, such as the adjuvant known as AS01.