THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
Hweixian Leong Penny,Edgar George Engleman,Nupur Bhattacharya
申请号:
US15464010
公开号:
US10039751B2
申请日:
2017.03.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An agent that increases local concentration of retinoic acid (RA) in the intestine through modifying enzymatic pathways involved in RA metabolism is administered in a dose effective to inhibit or reverse production of inflammatory mediators by intestinal dendritic cells and thereby reduce intestinal inflammation and tumor growth associated with intestinal inflammation.