Dong Liang,Lei Wu,Mathew Kizhakkekara Joseph,Jyothy Anie John
申请号:
US13200285
公开号:
US20120077824A1
申请日:
2011.09.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided herein is a pharmaceutical injectable formulation of itraconazole (10 mg/g) where the formulation comprises a solubilizer, a nonionic surfactant/emulsifier, a co-surfactant and a stabilizer. Further provided is a pharmaceutical formulation of itraconazole, said formulation comprising a solubilizer in a concentration of from about 20% to about 75%, a nonionic surfactant/emulsifier in a concentration of from about 20% to about 50%, a co-surfactant in a concentration from about 10% to about 45% and a stabilizer in a concentration of from about 1% to about 15%.