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Cationic polymers for antimicrobial applications and delivery of bioactive materials
专利权人:
发明人:
Daniel J. Coady,Amanda C. Engler,Kazuki Fukushima,James L. Hedrick,Jeremy P. K. Tan,Yi Yan Yang
申请号:
US14246045
公开号:
US09974303B2
申请日:
2014.04.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A cationic star polymer is disclosed of the general formula (1):wherein w′ is a positive number greater than or equal to 3, I′ is a dendritic polyester core covalently linked to w′ independent peripheral linear cationic polymer chains P′. Each of the chains P′ comprises a cationic repeat unit comprising i) a backbone functional group selected from the group consisting of aliphatic carbonates, aliphatic esters, aliphatic carbamates, aliphatic ureas, aliphatic thiocarbamates, aliphatic dithiocarbonates, and combinations thereof, and ii) a side chain comprising a quaternary amine group. The quaternary amine group comprises a divalent methylene group directly covalently linked to i) a positive charged nitrogen and ii) an aromatic ring.
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