Mark Kester,Thomas Stover,Tao Lowe,James H. Adair,Young Shin Kim
申请号：
US13673180
公开号：
US09326953B2
申请日:
2012.11.09
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
