UNIVERSITY OF DELAWARE;UNIVERSITY OF SOUTHERN CALIFORNIA
发明人:
申请号：
EP11810394.4
公开号：
EP2595967B1
申请日:
2011.07.21
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
A Diels-Alder adduct of a trans-cyclooctene with a tetrazine is provided, wherein the adduct bears a substituent labeled with a radionuclide. A method of producing a PET or other image of an organ in an animal or human includes forming the Diels-Alder adduct in the animal or human. Trans-cyclooctenes and tetrazines suitable for preparing the adducts are provided.
