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LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO siRNA CELL
专利权人:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人:
Hideyoshi Harashima,Yusuke Sato
申请号:
US16622109
公开号:
US20200129431A1
申请日:
2018.06.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A lipid membrane structure includes, as lipid components, a lipid compound represented by Formula (I):(R1)(R2)C(OH)—;(CH3)a—;(O—;CO)b—;X ; ;(I)[in the formula, a represents an integer of 3 to 5; b represents an integer of 0 or 1; R1 and R2 each independently represents a linear hydrocarbon group that may have —;CO—;O—;; and X represents a 5- to 7-membered non-aromatic heterocyclic group or a group represented by Formula (B) (in the formula, d represents an integer of 0 to 3, and R3 and R4 each independently represents a C1-4 alkyl group or a C2-4 alkenyl group, where, R3 and R4 may be bonded to each other to form a 5- to 7-membered non-aromatic heterocycle (where, one or two C1-4 alkyl groups or C2-4 alkenyl groups may be substituted on the ring)].
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