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PROPHYLACTIC OR THERAPEUTIC AGENT FOR NEUROPATHIC PAIN ASSOCIATED WITH GUILLAIN-BARRE SYNDROME
专利权人:
KYUSHU UNIVERSITY;NIPPON CHEMIPHAR CO., LTD.
发明人:
Toshiyasu IMAI,Toru KAWASAKI,Toru OGAWA,Kazuhide INOUE
申请号:
US15337384
公开号:
US20170065608A1
申请日:
2016.10.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A P2X4 receptor antagonist such as paroxetine, a diazepinedione derivative having the following formula (IX) is used as an agent for preventing or treating neuropathic pain associated with Guillain-Barré syndrome:wherein R1 is hydrogen, a C1-8 alkyl group, or the like;each of R2 and R3 is hydrogen, a C1-8 alkyl group, or the like;each of R4 and R5 is hydrogen or the like; andW is a five-membered or six-membered heterocyclic ring optionally having one or more substituents and comprising one to four nitrogen atoms as the members of the ring.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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