The present invention relates to depigmenting, lightening and/or whitening peptidic compounds of general formula (I)R1—X1—X2-Asp-Cys-Arg-X3—X4-(AA)p-R2.In addition, the present invention relates to, on the one hand, a cosmetic or pharmaceutical composition comprising at least one peptide of general formula (I), in a cosmetically or dermatologically acceptable medium and, on the other hand, its utilization to depigment, lighten and/or whiten the skin and prevent or treat hyperpigmentation blemishes as well as cutaneous signs due to photo-aging. Lastly, the invention applies to a cosmetic treatment method utilizing said peptidic compounds.