Bruce M. Spiegelman,Rajesh R. Rao,Jonathan Z. Long
申请号:
US14762375
公开号:
US10717992B2
申请日:
2014.01.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention provides compositions and methods for regulating thermogenesis and muscle inflammation through modulation of Metrnl and/or Metrn activity and/or expression. Also provided are methods for preventing or treating metabolic disorders and muscle inflammation disorders in a subject through modulation of Metrnl and/or Metrn activity and/or expression. Further provided are methods for identifying compounds that are capable of treating metabolic disorders and muscle inflammation disorders by modulating Metrnl and/or Metrn activity and/or expression.